Social determinants affect up to 80% of our health outside the realm of a traditional provider setting. Determinants impact health everywhere we live, learn, work, worship, and play; they are preventable, avoidable, and actionable, yet even as the U.S. spends more of its GDP on healthcare, health disparities continue to increase. This report aims to reframe social determinants as “root causes of health”, due to their significant impact on an individual’s ability to achieve positive health outcomes, offering examples of creative and replicable ways organizations have attempted to move the lever in changing the current healthcare landscape.